HPV test better than Pap when screening for cervical cancer

HPV test better than Pap when screening for cervical cancer

HPV test can be administered every five years, and catches more precancerous cells that traditional Pap smears. However, human papillomavirus (HPV)-based testing may be a more accurate way of testing for cervical cancer, new study results suggest. She has also stated that in the U.S.it has been a struggle to prove that the HPV testing would be enough to screen for cervical cancer, due to the lack of evidence and comparison between this test and the Pap smear.

"All women of childbearing age should be screened for cervical cancer", said lead researcher Dr. Gina Ogilvie, a professor in the School of Population and Public Health at the University of British Columbia, in Vancouver.

Of the women who tested negative on the HPV test, just 22 women showed grade 3 or worse cells, while the Pap smear group, found 52 women ended up with abnormal cells. So while the HPV test is more sensitive of a test, it isn't ideal and missed some women with early signs of cervical cancer.

Of note, the Canadian Task Force on Preventative Health Care differs from the US task force - it recommends Pap smear screening every three years between ages 30 and 69, citing weak evidence for screening women ages 25 to 29. Previous research has indicated that HPV testing alone or combined with a Pap smear is linked to increased detection of precancerous lesions in the first screening round, followed by a subsequent reduction in precancerous lesions.

Whether they receive a Pap test or an HPV test, the experience for patients is the same in their doctor's or nurse practitioners' office. The two groups were again tested with both the methods post of 4 years. The research compared the results from both tests and it might be that the HPV test is more accurate than the other.

At the beginning of this HPV FOCAL trial, half of the women obtained HPV testing and the other half received Pap smear. Despite the widespread use of cervical cancer screening with a Pap smear, it was estimated that approximately 12,820 women in the United States would develop, and 4210 would die, from cervical cancer in 2017. This method involves the direct analysis of the papillomavirus or HPV of the human that results in ninety-nine percent of the cervical cancers. According to the researchers, roughly one-third of surgeons said they often or always delayed surgery to obtain genetic testing.

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They also cautioned that more work needs to be done to assess the economic consequences of changing the screening model. In both the groups, the final co-testing discovered more abnormal cells within some of the women who initially tested negative.

The Pap test identifies abnormalities in cervical cells, flagging health-care providers to take a closer look to see if they are precancerous, and then take appropriate action.

Pap smear tests are also referred as Pap test or smear test or cervical smear test, in which Pap smear is prepared by collecting cells from outer cervix opening of the uterus and endocervix. "They usually take up to 10 years to progress to cancers, but the point is if you don't find them, and you don't know how long they've been there, there is a chance that they could progress to the invasive form of cervical cancer". "In fact, at the conclusion of the study, all HPV-negative women were tested with the Pap smear, which led to finding additional cases of pre-cancerous lesions".

The new study will probably "help push that along", said Wright of NewYork-Presbyterian/Columbia University Medical Center.

"If you tested everyone for HPV in their 20s, they are nearly all going to be positive, but there's going to be all of this intervention that's not needed", she says.

Medical students learn how to insert a speculum, part of the process of performing a Pap smear.

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